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NFkB 抗体 (C-Term)

This anti-NFkB antibody is a 兔 多克隆 antibody detecting NFkB in WB. Suitable for 人.
产品编号 ABIN5539290
发货至: 中国

Quick Overview for NFkB 抗体 (C-Term) (ABIN5539290)

抗原

See all NFkB 抗体
NFkB (Nuclear Factor kappa B (NFkB))

适用

  • 22
  • 10
  • 5
  • 4
  • 2
  • 2

宿主

  • 34
  • 6

克隆类型

  • 32
  • 8
多克隆

标记

  • 30
  • 7
  • 4
This NFkB antibody is un-conjugated

应用范围

  • 36
  • 32
  • 25
  • 20
  • 5
  • 4
  • 4
  • 3
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 911-937, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-937 amino acids from the C-terminal region of human NFKB(p105).

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    NFkB (Nuclear Factor kappa B (NFkB))

    别名

    NFKB

    背景

    This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    105 kDa

    基因ID

    4790

    UniProt

    P19838

    途径

    Ubiquitin Proteasome Pathway, S100 Proteins
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