SPG20 抗体 (C-Term)
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北京 101111
Quick Overview for SPG20 抗体 (C-Term) (ABIN5537986)
抗原
See all SPG20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 491-519, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-519 amino acids from the C-terminal region of human SPG20.
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亚型
- Ig Fraction
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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别名
- SPG20
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背景
- SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
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分子量
- 73 kDa
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基因ID
- 23111
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UniProt
- Q8N0X7
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途径
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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