-
- 抗原 See all SIGLEC12 抗体
- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
-
抗原表位
- AA 565-595, C-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SIGLEC12 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- 免疫原
- This SIGLEC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 565-595 amino acids from the C-terminal region of human SIGLEC12.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SIGLEC12 Primary Antibody
-
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 503-595) antibody
SIGLEC12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 27-141) antibodySIGLEC12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 20-210) antibodySIGLEC12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) antibodySIGLEC12 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 1-595) antibodySIGLEC12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 38-87) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 110-159) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 218-267) antibodySIGLEC12 适用: 人, Cow, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 20-210) antibodySIGLEC12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) (AA 22-218) antibodySIGLEC12 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- 抗原
- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
- 别名
- SIGLEC12 (SIGLEC12 产品)
- 别名
- S2V antibody, SIGLECL1 antibody, SLG antibody, Siglec-XII antibody, sialic acid binding Ig like lectin 12 (gene/pseudogene) antibody, sialic acid binding Ig like lectin 12 antibody, sialic acid binding Ig-like lectin 12 antibody, SIGLEC12 antibody
- 背景
- Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. SIGLEC12 is a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. This protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor.
- 分子量
- 65 kDa
- 基因ID
- 89858
- UniProt
- Q96PQ1
-
You are here:
