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SFTPB 抗体 (AA 129-158)

This anti-SFTPB antibody is a 兔 多克隆 antibody detecting SFTPB in WB. Suitable for 人.
产品编号 ABIN5537428
发货至: 中国

Quick Overview for SFTPB 抗体 (AA 129-158) (ABIN5537428)

抗原

See all SFTPB 抗体
SFTPB (Surfactant Protein B (SFTPB))

适用

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宿主

  • 40
  • 10

克隆类型

  • 42
  • 8
多克隆

标记

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This SFTPB antibody is un-conjugated

应用范围

  • 46
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Western Blotting (WB)
  • 抗原表位

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    AA 129-158

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SFTPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the Central region of human SFTPB.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SFTPB (Surfactant Protein B (SFTPB))

    别名

    SFTPB

    背景

    SFTPB is the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.

    分子量

    42 kDa

    基因ID

    6439

    UniProt

    P07988
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