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KDM5B 抗体 (N-Term)

This anti-KDM5B antibody is a 兔 多克隆 antibody detecting KDM5B in WB. Suitable for 小鼠.
产品编号 ABIN5537034
发货至: 中国

Quick Overview for KDM5B 抗体 (N-Term) (ABIN5537034)

抗原

See all KDM5B 抗体
KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

适用

  • 42
  • 21
  • 18
  • 1
  • 1
小鼠

宿主

  • 41
  • 7

克隆类型

  • 42
  • 6
多克隆

标记

  • 23
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KDM5B antibody is un-conjugated

应用范围

  • 37
  • 17
  • 17
  • 13
  • 13
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 192-224, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This JARID1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-224 amino acids from the N-terminal region of human JARID1B.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

    别名

    JARID1B

    背景

    Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.

    分子量

    176 kDa

    基因ID

    10765

    UniProt

    Q9UGL1

    途径

    Warburg Effect
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