USP20 抗体 (AA 310-339)
Quick Overview for USP20 抗体 (AA 310-339) (ABIN5534787)
抗原
See all USP20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-339
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This USP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-339 amino acids from the Central region of human USP20.
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亚型
- Ig Fraction
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anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibody
USP20 适用: 人, 犬, 兔, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 犬, 兔, 马, 小鸡, Cow, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (C-Term) antibodyVerified USP20 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 361-410) antibodyUSP20 适用: 人, 大鼠, 兔, 小鸡, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 814-844), (C-Term) antibodyUSP20 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4351 unconjugated
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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别名
- USP20
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背景
- Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'-and 'Lys-63'-linked polyubiquitin chains.
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分子量
- 102 kDa
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基因ID
- 10868
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UniProt
- Q9Y2K6
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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