SIGLEC6 抗体 (C-Term)
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Quick Overview for SIGLEC6 抗体 (C-Term) (ABIN5534686)
抗原
See all SIGLEC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 381-412, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SIGLEC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-412 amino acids from the C-terminal region of human SIGLEC6.
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亚型
- Ig Fraction
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anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 27-347) antibody
SIGLEC6 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3C11C12G1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) antibodySIGLEC6 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 1-437) antibodySIGLEC6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 371-453) antibodySIGLEC6 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 76-269) antibodySIGLEC6 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (Internal Region) antibodyVerified SIGLEC6 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 180-229) antibodySIGLEC6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 1-437) antibodySIGLEC6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (C-Term) antibodySIGLEC6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 74-123) antibodySIGLEC6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
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别名
- SIGLEC6
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背景
- SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.
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分子量
- 50 kDa
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基因ID
- 946
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UniProt
- O43699
抗原
-
