This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This CHD1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-590 amino acids from the Central region of human CHD1L.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
CHD1L
(Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
CHD1L antibody, ALC1 antibody, CHDL antibody, 4432404A22Rik antibody, Alc1 antibody, Snf2p antibody, zgc:56084 antibody, chromodomain helicase DNA binding protein 1 like antibody, chromodomain helicase DNA binding protein 1-like antibody, CHD1L antibody, chd1l antibody, Chd1l antibody
背景
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].