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RFXANK 抗体 (AA 94-123)

The 兔 多克隆 anti-RFXANK antibody is suitable to detect RFXANK in samples from 人. It has been validated for WB.
产品编号 ABIN5533710
发货至: 中国
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Quick Overview for RFXANK 抗体 (AA 94-123) (ABIN5533710)

抗原

See all RFXANK 抗体
RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

适用

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宿主

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克隆类型

  • 23
  • 10
多克隆

标记

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This RFXANK antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 7
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    AA 94-123

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RFXANK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human RFXANK.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

    别名

    RFXANK

    背景

    Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.

    分子量

    28 kDa

    基因ID

    8625

    UniProt

    O14593
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