DHCR7 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for DHCR7 抗体 (C-Term) (ABIN5533223)
抗原
See all DHCR7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 437-463, C-Term
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This DHCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.
-
亚型
- Ig Fraction
-
-
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 437-463), (C-Term) antibody
DHCR7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17942 unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 1-475) antibodyDHCR7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 63-147) antibodyDHCR7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 351-450) antibodyDHCR7 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
For IF starting dilution is: 1:25
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
-
别名
- DHCR7
-
背景
- This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
-
分子量
- 54 kDa
-
基因ID
- 1717
-
UniProt
- Q9UBM7
抗原
-
