Pyruvate Kinase 抗体 (C-Term)
Quick Overview for Pyruvate Kinase 抗体 (C-Term) (ABIN5532984)
抗原
See all Pyruvate Kinase (PK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 476-505, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
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免疫原
- This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).
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亚型
- Ig Fraction
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应用备注
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For WB starting dilution is: 1:1000
For IF starting dilution is: 1:200
For IHC-P starting dilution is: 1:50~1:100 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Pyruvate Kinase (PK)
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别名
- Pyruvate Kinase
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背景
- There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
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分子量
- 58 kDa
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基因ID
- 5315
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UniProt
- P14618
抗原
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