This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This NACC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human NACC2.
BTBD14A
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 488
应用备注
For WB starting dilution is: 1:1000
限制
仅限研究用
状态
Liquid
浓度
0.3 mg/mL
缓冲液
Supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NACC2 antibody, BTBD14A antibody, BEND9 antibody, BTBD14 antibody, BTBD31 antibody, Btbd14a antibody, 0610020I02Rik antibody, AI448087 antibody, C030048H19Rik antibody, NACC family member 2 antibody, nucleus accumbens-associated protein 2-like antibody, nucleus accumbens associated 2, BEN and BTB (POZ) domain containing antibody, NACC2 antibody, LOC100354269 antibody, Nacc2 antibody
背景
BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.