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ADRA2C 抗体 (C-Term)

This anti-ADRA2C antibody is a 兔 多克隆 antibody detecting ADRA2C in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN5532816
发货至: 中国

Quick Overview for ADRA2C 抗体 (C-Term) (ABIN5532816)

抗原

See all ADRA2C 抗体
ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADRA2C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 22
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    AA 354-382, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ADRA2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-382 amino acids from the C-terminal region of human ADRA2C.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

    别名

    ADRA2C

    背景

    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

    分子量

    50 kDa

    基因ID

    152

    UniProt

    P18825

    途径

    EGFR Signaling Pathway, cAMP Metabolic Process
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