ADD3 抗体 (C-Term)
Quick Overview for ADD3 抗体 (C-Term) (ABIN5532513)
抗原
See all ADD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 552-580, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ADD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 552-580 amino acids from the C-terminal region of human ADD3.
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亚型
- Ig Fraction
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anti-Adducin 3 (Gamma) (ADD3) (AA 462-560) antibody
ADD3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (C-Term) antibodyADD3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, 斑马鱼 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (C-Term) antibodyADD3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, 斑马鱼, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (C-Term) antibodyADD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adducin 3 (Gamma) (ADD3) (Internal Region) antibodyADD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ADD3 (Adducin 3 (Gamma) (ADD3))
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别名
- ADD3
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背景
- Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known.
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分子量
- 79 kDa
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基因ID
- 120
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UniProt
- Q9UEY8
抗原
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