TEAD2 抗体 (AA 267-295)
Quick Overview for TEAD2 抗体 (AA 267-295) (ABIN5532239)
抗原
See all TEAD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 267-295
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TEAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the Central region of human TEAD2.
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亚型
- Ig Fraction
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anti-TEA Domain Family Member 2 (TEAD2) (Internal Region) antibody
Verified TEAD2 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) antibodyTEAD2 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 404C5a unconjugated
anti-TEA Domain Family Member 2 (TEAD2) antibodyTEAD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (Internal Region) antibodyTEAD2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) antibodyTEAD2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 218-307) antibodyTEAD2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 1-447) antibodyTEAD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (N-Term) antibodyTEAD2 适用: 人, Cow, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 71-120) antibodyTEAD2 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (N-Term) antibodyTEAD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TEAD2 (TEA Domain Family Member 2 (TEAD2))
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别名
- TEAD2
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背景
- Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
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分子量
- 49 kDa
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基因ID
- 8463
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UniProt
- Q15562
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途径
- Regulation of Lipid Metabolism by PPARalpha, Tube Formation
抗原
-
