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Stanniocalcin 2 抗体 (N-Term)

This anti-Stanniocalcin 2 antibody is a 兔 多克隆 antibody detecting Stanniocalcin 2 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN5532193
发货至: 中国

Quick Overview for Stanniocalcin 2 抗体 (N-Term) (ABIN5532193)

抗原

See all Stanniocalcin 2 (STC2) 抗体
Stanniocalcin 2 (STC2)

适用

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人, 小鼠

宿主

  • 60
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克隆类型

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多克隆

标记

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This Stanniocalcin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    AA 16-46, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

    免疫原

    This Stanniocalcin-2 (STC2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human Stanniocalcin-2 (STC2).

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Stanniocalcin 2 (STC2)

    别名

    Stanniocalcin-2

    背景

    STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.

    分子量

    33 kDa

    基因ID

    8614

    UniProt

    O76061

    途径

    Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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