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SNX6 抗体 (N-Term)

SNX6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532129
发货至: 中国
  • 抗原 See all SNX6 抗体
    SNX6 (Sorting Nexin 6 (SNX6))
    抗原表位
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-110, N-Term
    适用
    • 35
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 27
    • 9
    克隆类型
    • 27
    • 9
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNX6 antibody is un-conjugated
    应用范围
    • 24
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This SNX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human SNX6.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SNX6 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SNX6 (Sorting Nexin 6 (SNX6))
    别名
    SNX6 (SNX6 产品)
    别名
    MGC75952 antibody, MGC80251 antibody, im:7146294 antibody, wu:fa55b10 antibody, zgc:110798 antibody, MSTP010 antibody, TFAF2 antibody, 2010006G21Rik antibody, 2610032J07Rik antibody, 2810425K19Rik antibody, AU018928 antibody, C85963 antibody, sorting nexin 6 antibody, sorting nexin 6 L homeolog antibody, snx6 antibody, snx6.L antibody, SNX6 antibody, Snx6 antibody
    背景
    SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
    分子量
    47 kDa
    基因ID
    58533
    UniProt
    Q9UNH7
    途径
    EGFR Signaling Pathway
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