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Prohibitin 2 抗体 (N-Term)

This anti-Prohibitin 2 antibody is a 兔 多克隆 antibody detecting Prohibitin 2 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN5531960
发货至: 中国

Quick Overview for Prohibitin 2 抗体 (N-Term) (ABIN5531960)

抗原

See all Prohibitin 2 (PHB2) 抗体
Prohibitin 2 (PHB2)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prohibitin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
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    AA 66-95, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This REA (PHB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human REA (PHB2).

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    14 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Prohibitin 2 (PHB2)

    别名

    REA

    背景

    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.

    分子量

    33 kDa

    基因ID

    11331

    UniProt

    Q99623

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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