PDZK1 抗体 (AA 196-224)
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北京 101111
Quick Overview for PDZK1 抗体 (AA 196-224) (ABIN5531816)
抗原
See all PDZK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 196-224
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDZK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human PDZK1.
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亚型
- Ig Fraction
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应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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别名
- PDZK1
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背景
- A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
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分子量
- 57 kDa
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基因ID
- 5174
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UniProt
- Q5T2W1
抗原
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