SUPT5H 抗体 (AA 395-424)
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北京 101111
Quick Overview for SUPT5H 抗体 (AA 395-424) (ABIN5531040)
抗原
See all SUPT5H 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 395-424
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SUPT5H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human SUPT5H.
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亚型
- Ig Fraction
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anti-Transcription Elongation Factor SPT5 (SUPT5H) (AA 981-1087) antibody
SUPT5H 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Transcription Elongation Factor SPT5 (SUPT5H) antibodyKD Validated SUPT5H 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4220 unconjugated Recombinant Antibody
anti-Transcription Elongation Factor SPT5 (SUPT5H) (AA 892-941) antibodySUPT5H 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor SPT5 (SUPT5H) (C-Term) antibodySUPT5H 适用: 人, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor SPT5 (SUPT5H) (AA 125-425) antibodySUPT5H 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor SPT5 (SUPT5H) (AA 396-445) antibodySUPT5H 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Elongation Factor SPT5 (SUPT5H) (Middle Region) antibodySUPT5H 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.3 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))
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别名
- SUPT5H
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背景
- Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
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分子量
- 121 kDa
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基因ID
- 6829
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UniProt
- O00267
抗原
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