PDCD1LG2 抗体
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北京 101111
Quick Overview for PDCD1LG2 抗体 (ABIN5526895)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD273 Purified
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交叉反应 (详细)
- Human
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产品特性
- The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- human CD273 cDNA
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亚型
- IgG2a, kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- CD273
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背景
- Programmed cell death 1 ligand 2,CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.,PDCD1LG2, B7DC, Btdc, PDL2, PDCD1L2, bA574F11.2, Butyrophilin, B7-DC,
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基因ID
- 80380
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UniProt
- Q9BQ51
抗原
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