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PDCD1LG2 抗体

The 小鼠 单克隆 anti-PDCD1LG2 antibody (Clone 24F-10C12) (ABIN5526895) specifically detects PDCD1LG2 in FACS 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN5526895
发货至: 中国
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Quick Overview for PDCD1LG2 抗体 (ABIN5526895)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

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宿主

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小鼠

克隆类型

  • 86
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单克隆

标记

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This PDCD1LG2 antibody is un-conjugated

应用范围

  • 70
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Flow Cytometry (FACS), Immunohistochemistry (IHC)

克隆位点

24F-10C12
  • 原理

    Anti-Hu CD273 Purified

    交叉反应 (详细)

    Human

    产品特性

    The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    human CD273 cDNA

    亚型

    IgG2a, kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    CD273

    背景

    Programmed cell death 1 ligand 2,CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.,PDCD1LG2, B7DC, Btdc, PDL2, PDCD1L2, bA574F11.2, Butyrophilin, B7-DC,

    基因ID

    80380

    UniProt

    Q9BQ51
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