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TIMP1 抗体 (AA 24-207)

Name: TIMP1 抗体 (AA 24-207)
SKU: ABIN5519064
Availability: OutOfStock

TIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of TIMP1 using anti-TIMP1 antibody . (TIMP1 抗体 (AA 24-207))

1 image

(14 references)

产品编号 ABIN5519064

发货至: 中国

Datasheet as PDF

抗原 See all TIMP1 抗体

TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
抗原表位
18

15

14

12

9

7

5

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 24-207
适用
120

57

54

22

6

4

4

4

2

2

1

1
人, 大鼠, 小鼠
宿主
124

30

5

1

1
兔
Compatible Secondaries
克隆类型
125

35
多克隆
标记
77

16

13

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
This TIMP1 antibody is un-conjugated
应用范围
101

58

39

25

25

19

18

17

16

14

9

7

6

4

4

4

4

3

2

1

1

1

1
Western Blotting (WB), ELISA

原理

Anti-TIMP1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-TIMP1 Antibody Picoband® (ABIN5519064). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human TIMP1 recombinant protein (Position: C24-A207).

亚型

IgG

Top Product

Discover our top product TIMP1 Primary Antibody
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 103-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 41-70), (N-Term) antibody
TIMP1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB15494 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 157-188), (C-Term) antibody
TIMP1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB14602 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-207) antibody
TIMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibody
TIMP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibody
TIMP1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8B4E9 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) antibody
TIMP1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibody
TIMP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 131-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-217) antibody
TIMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Anderson, C. L., Brown, C. J. Polymorphic X-chromosome inactivation of the human TIMP1 gene. Am. J. Hum. Genet. 65: 699-708, 1999. 2. Zeiss, C. J., Acland, G. M., Aguirre, G. D., Ray, K. TIMP-1 expression is increased in X-linked progressive retinal atrophy despite its exclusion as a candidate gene. Gene 225: 67-75, 1998.

说明

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Liu, Liu, Tan, Tang, Long, Li, Liang, Chu, Yang: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).

"Retraction: Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192465, (2018) (PubMed).

Wang, Jiang, Xue: "Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1." in: African health sciences, Vol. 16, Issue 2, pp. 542-53, (2017) (PubMed).

Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

Chen, Zhang, Ma, Huang, Shao, Wu, Wang: "Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143868, (2016) (PubMed).

Fan, Jiang, Li, Fang, Xu, Zheng: "MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elastic fibers correlate with disease progression in a hamster model of tongue cancer." in: Oncology letters, Vol. 11, Issue 1, pp. 63-68, (2016) (PubMed).

Di, Nie, Chen: "Matrix metalloproteinase-9 and vascular endothelial growth factor expression change in experimental retinal neovascularization." in: International journal of ophthalmology, Vol. 9, Issue 6, pp. 804-8, (2016) (PubMed).

Deng, Ling, Liu, Zhao, Lv: "Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 992-998, (2015) (PubMed).

Yin, Li, Gao, Li, Li: "Andrographolide plays an important role in bleomycin-induced pulmonary fibrosis treatment." in: International journal of clinical and experimental medicine, Vol. 8, Issue 8, pp. 12374-81, (2015) (PubMed).

Xu, Dai, Liu, Liu, Song, Li, Chen, Lin: "Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1065-1074, (2014) (PubMed).

Zhong, Wang, Jian: "Expression of matrix metalloproteinases-8 and -9 and their tissue inhibitor in the condyles of diabetic rats with mandibular advancement." in: Experimental and therapeutic medicine, Vol. 8, Issue 5, pp. 1357-1364, (2014) (PubMed).

Ma, Ma, Ma, Sun, Yu, Wang, Li, Ding: "The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 710870, (2014) (PubMed).

Li, Liu, Zhang, Zhu, He, Xiao: "Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis." in: World journal of gastroenterology, Vol. 11, Issue 16, pp. 2438-43, (2005) (PubMed).

Yang, Xie, Geng, Luo, Han, Cheng: "Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats." in: World journal of gastroenterology, Vol. 11, Issue 32, pp. 4953-6, (2005) (PubMed).
抗原

TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

别名

TIMP1 (TIMP1 产品)

背景

Synonyms: Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP,
Tissue Specificity: Detected in rheumatoid synovial fluid (at protein level).
Background: TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).

分子量

23 kDa

基因ID

7076

UniProt

P01033