SAG 抗体 (AA 193-405)
Quick Overview for SAG 抗体 (AA 193-405) (ABIN5519058)
抗原
See all SAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 193-405
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原理
- Anti-Retinal S antigen/SAG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Retinal S antigen/SAG Antibody Picoband® (ABIN5519058). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Retinal S antigen recombinant protein (Position: R193-E405).
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亚型
- IgG
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anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 1-405) antibody
SAG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 4-249) antibodySAG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) antibodySAG 适用: 人, 大鼠, Cow, Pig WB, ICC, IF, IHC (fro) 宿主: 小鼠 Monoclonal PDS-1 unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (Internal Region) antibodySAG 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 369-418) antibodySAG 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 273-307) antibodySAG 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53546 unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) antibodySAG 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 1-405) antibodySAG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) antibodySAG 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S128 unconjugated
anti-S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 369-418), (pSer412) antibodySAG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Calabrese, G., Sallese, M., Stornaiuolo, A., Stuppia, L., Palka, G., De Blasi, A. Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes. Genomics 23: 286-288, 1994. 2. Yamaki, K., Tsuda, M., Kikuchi, T., Chen, K.-H., Huang, K.-P., Shinohara, T. Structural organization of the human S-antigen gene: cDNA, amino acid, intron, exon, promoter, in vitro transcription, retina, and pineal gland. J. Biol. Chem. 265: 20757-20762, 1990. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
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别名
- SAG
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背景
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Synonyms: S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin, SAG,
Tissue Specificity: Retina and pineal gland.
Background: S-arrestin is a protein that in humans is encoded by the SAG gene. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
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分子量
- 45-55 kDa
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基因ID
- 6295
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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