Oncostatin M 抗体 (AA 25-206)
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- 抗原 See all Oncostatin M (OSM) 抗体
- Oncostatin M (OSM)
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抗原表位
- AA 25-206
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Oncostatin M antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Oncostatin M detection. Tested with WB, ELISA(Cap) in Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Oncostatin M detection. Tested with WB, ELISA(Cap) in Mouse,Rat.
Gene Name: oncostatin M
Protein Name: Oncostatin-M - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived mouse Oncostatin M recombinant protein (Position: N25-R206).
- 亚型
- IgG
- Top Product
- Discover our top product OSM Primary Antibody
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- 应用备注
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Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Oncostatin M (OSM)
- 别名
- Osm (OSM 产品)
- 别名
- OSM antibody, OncoM antibody, oncostatin M antibody, OSM antibody, Osm antibody
- 背景
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OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. It has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.
Synonyms: Oncostatin-M, OSM, Osm - 基因ID
- 18413
- UniProt
- P53347
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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