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IL17F 抗体 (AA 31-163)

This anti-IL17F antibody is a 兔 多克隆 antibody detecting IL17F in WB 和 ELISA. Suitable for 人 和 大鼠.
产品编号 ABIN5519013
发货至: 中国

Quick Overview for IL17F 抗体 (AA 31-163) (ABIN5519013)

抗原

See all IL17F 抗体
IL17F (Interleukin 17F (IL17F))

适用

  • 86
  • 32
  • 19
人, 大鼠

宿主

  • 88
  • 26
  • 2

克隆类型

  • 91
  • 24
  • 1
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL17F antibody is un-conjugated

应用范围

  • 83
  • 54
  • 35
  • 21
  • 19
  • 12
  • 8
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
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  • 2
  • 1
  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 23
    • 6
    • 6
    • 4
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    • 2
    • 2
    • 2
    • 1
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    AA 31-163

    原理

    Anti-IL17F Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-IL17F Antibody Picoband® (ABIN5519013). Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human IL17F recombinant protein (Position: R31-Q163).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Starnes, T., Robertson, M. J., Sledge, G., Kelich, S., Nakshatri, H., Broxmeyer, H. E., Hromas, R. Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production. J. Immun. 167: 4137-4140, 2001. 2. Wang, X., Zhang, Y., Yang, X. O., Nurieva, R. I., Chang, S. H., Ojeda, S. S., Kang, H. S., Schluns, K. S., Gui, J., Jetten, A. M., Dong, C. Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2. Immunity 36: 23-31, 2012.

    说明

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL17F (Interleukin 17F (IL17F))

    别名

    IL17F

    背景

    Synonyms: Interleukin-17F, IL-17F, Cytokine ML-1, IL17F,

    Tissue Specificity: Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.

    Background: Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.

    分子量

    18 kDa, 30 kDa

    基因ID

    112744

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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