IL15RA 抗体 (AA 31-174)
Quick Overview for IL15RA 抗体 (AA 31-174) (ABIN5519011)
抗原
See all IL15RA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-174
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原理
- Anti-IL15RA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IL15RA Antibody Picoband® (ABIN5519011). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human IL15RA recombinant protein (Position: I31-T174).
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亚型
- IgG
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anti-Interleukin 15 Receptor, alpha (IL15RA) (AA 31-205) antibody
IL15RA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F10D9 unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) (AA 31-205) antibodyIL15RA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) antibodyIL15RA 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) (AA 31-130) antibodyIL15RA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) (AA 31-130) antibodyIL15RA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) (Internal Region) antibodyIL15RA 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) antibodyIL15RA 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal unconjugated
anti-Interleukin 15 Receptor, alpha (IL15RA) (Extracellular Domain) antibody (Carboxyfluorescein (CFS))IL15RA 适用: 小鼠 FACS 宿主: 山羊 Polyclonal Carboxyfluorescein (CFS)
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA(Cap), 1-5 μg/mL
1. Anderson, D. M., Kumaki, S., Ahdieh, M., Bertles, J., Tometsko, M., Loomis, A., Giri, J., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Valentine, V., Shapiro, D. N., Morris, S. W., Park, L. S., Cosman, D. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J. Biol. Chem. 270: 29862-29869, 1995. 2. Brilot, F., Strowig, T., Roberts, S. M., Arrey, F., Munz, C. NK cell survival mediated through the regulatory synapse with human DCs requires IL-15R-alpha. J. Clin. Invest. 117: 3316-3329, 2007. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
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别名
- IL15RA
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背景
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Synonyms: Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD215, Soluble interleukin-15 receptor subunit alpha, sIL-15 receptor subunit alpha, sIL-15R-alpha, sIL-15RA, IL15RA,
Tissue Specificity: Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
Background: Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
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分子量
- 28 kDa
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基因ID
- 3601
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UniProt
- Q13261
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途径
- JAK/STAT Signaling
抗原
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