SRY 抗体 (Middle Region)
Quick Overview for SRY 抗体 (Middle Region) (ABIN5518959)
抗原
See all SRY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-130, Middle Region
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原理
- Anti-SRY Antibody Picoband®
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序列
- ISKQLGYQWK MLTEAEKWPF FQEAQKLQAM HREKYPNYKY R
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SRY Antibody Picoband® (ABIN5518959). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SRY.
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亚型
- IgG
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anti-Sex Determining Region Y (SRY) antibody
SRY 适用: 人 WB 宿主: 小鼠 Monoclonal 1H10 unconjugated
anti-Sex Determining Region Y (SRY) (AA 1-204) antibodySRY 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) (AA 52-82) antibodySRY 适用: 人 WB 宿主: 兔 Polyclonal RB53824 unconjugated
anti-Sex Determining Region Y (SRY) (AA 1-204) antibodySRY 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) (Internal Region) antibodySRY 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) antibodySRY 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Sex Determining Region Y (SRY) (Internal Region) antibodySRY 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sex Determining Region Y (SRY) (AA 81-112) antibodySRY 适用: 人 WB 宿主: 兔 Polyclonal RB53826 unconjugated
anti-Sex Determining Region Y (SRY) (C-Term) antibodySRY 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Biason-Lauber A, Konrad D, Meyer M, DeBeaufort C, Schoenle EJ (May 2009). "Ovaries and female phenotype in a girl with 46,XY karyotype and mutations in the CBX2 gene". Am. J. Hum. Genet. 84 (5): 658-63. 2. Margarit E, Coll MD, Oliva R, Gómez D, Soler A, Ballesta F (January 2000). "SRY gene transferred to the long arm of the X chromosome in a Y-positive XX true hermaphrodite". Am. J. Med. Genet. 90 (1): 25-8. 3. Polanco JC, Koopman P (February 2007). "Sry and the hesitant beginnings of male development". Dev. Biol. 302 (1): 13-24. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SRY (Sex Determining Region Y (SRY))
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别名
- SRY
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背景
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Synonyms: Sex-determining region Y protein,Testis-determining factor,SRY,TDF,
Tissue Specificity: Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen. .
Background: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
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分子量
- 26 kDa
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基因ID
- 6736
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UniProt
- Q05066
抗原
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