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SLC6A1 抗体 (N-Term)

This anti-SLC6A1 antibody is a 兔多克隆 antibody detecting SLC6A1 in WB. Suitable for 人, 大鼠和小鼠.

Western blot analysis of SLC6A1 using anti-SLC6A1 antibody . (SLC6A1 抗体 (N-Term))

1 image

产品编号 ABIN5518957

发货至: 中国

Quick Overview for SLC6A1 抗体 (N-Term) (ABIN5518957)

抗原

See all SLC6A1 (GAT1) 抗体

SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

适用

29
26
19
5
4
4
4
4
4
2
2
1
1
1

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

31
1
1
1
1
1
1
1

This SLC6A1 antibody is un-conjugated

应用范围

31
13
10
4
4
3
3
1
1
1
1

Western Blotting (WB)

Discover our top product GAT1 Primary Antibody

抗原表位
5

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 23-54, N-Term

原理

Anti-GABA Transporter 1/GAT 1/SLC6A1 Antibody Picoband®

序列

ANDKPKTLVV KVQKKAADLP DRDTWKGRFD FL

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-GABA Transporter 1/GAT 1/SLC6A1 Antibody Picoband® (ABIN5518957). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human SLC6A1, different from the related mouse and rat sequences by two amino acids.

亚型

IgG
anti-GABA Transporter 1 (GAT1) (AA 585-599) antibody
GAT1 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) antibody
GAT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) antibody
GAT1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) (Internal Region) antibody
GAT1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) antibody
GAT1 适用: 大鼠, 小鼠 WB, IHC, ICC, IP 宿主: 豚鼠 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) (C-Term) antibody
GAT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) (Middle Region) antibody
GAT1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) (C-Term) antibody
GAT1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) antibody
GAT1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-GABA Transporter 1 (GAT1) (AA 251-300) antibody
GAT1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. Carvill, G. L., McMahon, J. M., Schneider, A., Zemel, M., Myers, C. T., Saykally, J., Nguyen, J., Robbiano, A., Zara, F., Specchio, N., Mecarelli, O., Smith, R. L., and 13 others. Mutations in the GABA transporter SLC6A1 cause epilepsy with myoclonic-atonic seizures. Am. J. Hum. Genet. 96: 808-815, 2015. Huang, F., Shi, L. J., 2. Cope, D. W., Di Giovanni, G., Fyson, S. J., Orban, G., Errington, A. C., Lorincz, M. L., Gould, T. M., Carter, D. A., Crunelli, V. Enhanced tonic GABA-A inhibition in typical absence epilepsy. Nature Med. 15: 1392-1398, 2009. 3. Heng, H. H. Q., Fei, J., Guo, L.-H. Assignment of the human GABA transporter gene (GABATHG) locus to chromosome 3p24-p25. Genomics 29: 302-304, 1995.

说明

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

别名

SLC6A1

背景

Synonyms: Sodium- and chloride-dependent GABA transporter 1,GAT-1,Solute carrier family 6 member 1,SLC6A1,GABATR, GABT1, GAT1,
Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.
Background: GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in the cerebrum and cerebellum. The stoichiometry for GABA Transporter 1 is 2 Na+: 1 Cl-: 1 GABA. The activity of GAT1 is largely dependent on the presence of Na+, while Cl- assists by increasing the ability for GAT-1 to uptake GABA.

分子量

88 kDa

基因ID

6529

UniProt

P30531

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