SIX Homeobox 6 抗体 (AA 188-246)
Quick Overview for SIX Homeobox 6 抗体 (AA 188-246) (ABIN5518956)
抗原
See all SIX Homeobox 6 (SIX6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 188-246
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原理
- Anti-Homeobox protein SIX6 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Homeobox protein SIX6 Antibody Picoband® (ABIN5518956). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human SIX6 recombinant protein (Position: A188-I246). Human SIX6 shares 91.5% amino acid (aa) sequence identity with mouse SIX6.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Aijaz, S., Clark, B. J., Williamson, K., van Heyningen, V., Morrison, D., FitzPatrick, D., Collin, R., Ragge, N., Christoforou, A., Brown, A., Hanson, I. Absence of SIX6 mutations in microphthalmia, anophthalmia, and coloboma. Invest. Ophthal. Vis. Sci. 45: 3871-3876, 2004. 2. Aldahmesh, M. A., Khan, A. O., Hijazi, H., Alkuraya, F. S. Homozygous truncation of SIX6causes complex microphthalmia in humans. (Letter) Clin. Genet. 84: 198-199, 2013. 3. Gallardo, M. E., Rodriguez de Cordoba, S., Schneider, A. S., Dwyer, M. A., Ayuso, C., Bovolenta, P. Analysis of the developmental SIX6 homeobox gene in patients with anophthalmia/microphthalmia. (Letter) Am. J. Med. Genet. 129A: 92-94, 2004. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SIX Homeobox 6 (SIX6)
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别名
- SIX6
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背景
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Synonyms: Homeobox protein SIX6,Homeodomain protein OPTX2,Optic homeobox 2,Sine oculis homeobox homolog 6,SIX6,OPTX2, SIX9,
Tissue Specificity: Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.
Background: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).
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分子量
- 28 kDa
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基因ID
- 4990
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UniProt
- O95475
抗原
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