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FOXP2 抗体 (AA 637-715)

This anti-FOXP2 antibody is a 兔 多克隆 antibody detecting FOXP2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5518915
发货至: 中国

Quick Overview for FOXP2 抗体 (AA 637-715) (ABIN5518915)

抗原

See all FOXP2 抗体
FOXP2 (Forkhead Box P2 (FOXP2))

适用

  • 45
  • 23
  • 13
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33
  • 7
  • 3
  • 2
  • 1

克隆类型

  • 35
  • 10
  • 1
多克隆

标记

  • 32
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXP2 antibody is un-conjugated

应用范围

  • 31
  • 25
  • 13
  • 8
  • 7
  • 6
  • 5
  • 2
Western Blotting (WB)
  • 抗原表位

    • 11
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 637-715

    原理

    Anti-FOXP2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-FOXP2 Antibody Picoband® (ABIN5518915). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human FOXP2 recombinant protein (Position: L637-E715). Human FOXP2 shares 100% amino acid (aa) sequence identity with both mouse and rat FOXP2.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Bruce, H. A., Margolis, R. L. FOXP2: novel exons, splice variants, and CAG repeat length stability. Hum. Genet. 111: 136-144, 2002. 2. Enard, W., Przeworski, M., Fisher, S. E., Lai, C. S. L., Wiebe, V., Kitano, T., Monaco, A. P., Paabo, S. Molecular evolution of FOXP2, a gene involved in speech and language. Nature 418: 869-872, 2002. 3. Haesler, S., Wada, K., Nshdejan, A., Morrisey, E. E., Lints, T., Jarvis, E. D., Scharff, C. FoxP2expression in avian vocal learners and non-learners. J. Neurosci. 24: 3164-3175, 2004.

    说明

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FOXP2 (Forkhead Box P2 (FOXP2))

    别名

    FOXP2

    背景

    Synonyms: Forkhead box protein P2,CAG repeat protein 44,Trinucleotide repeat-containing gene 10 protein,FOXP2,CAGH44, TNRC10,

    Tissue Specificity: Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. .

    Background: Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene. This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind ly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia.

    分子量

    90 kDa

    基因ID

    93986

    UniProt

    O15409
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