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TIMP3 抗体 (Middle Region)

Cited in 2+ publications. This anti-TIMP3 antibody is a 兔 多克隆 antibody detecting TIMP3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5518878
发货至: 中国
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Room 801-803
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Quick Overview for TIMP3 抗体 (Middle Region) (ABIN5518878)

抗原

See all TIMP3 抗体
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TIMP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 107-141, Middle Region

    原理

    Anti-TIMP3 Antibody

    序列

    RVYDGKMYTG LCNFVERWDQ LTLSQRKGLN YRYHL

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TIMP3 Antibody (ABIN5518878). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human TIMP3, different from the related mouse and rat sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    ELISA, 0.1-0.5 μg/mL, -
    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Guan, Zhang, Song, Dai: "Promoter methylation and expression of TIMP3 gene in gastric cancer." in: Diagnostic pathology, Vol. 8, pp. 110, (2014) (PubMed).

    Bai, Yi, Li, Sui: "Clinicopathologic significance of BAG1 and TIMP3 expression in colon carcinoma." in: World journal of gastroenterology, Vol. 13, Issue 28, pp. 3883-5, (2007) (PubMed).

  • 抗原

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    别名

    TIMP3

    背景

    Synonyms: Metalloproteinase inhibitor 3,Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3,TIMP3,

    Tissue Specificity: Ubiquitously expressed.

    Background: Metalloproteinase inhibitor 3 is a protein that in humans is encoded by the TIMP3 gene. It is mapped to 22q12.1-q13.2. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of theextracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

    分子量

    24 kDa

    UniProt

    P35625
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