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PPIA 抗体 (AA 116-165)

This anti-PPIA antibody is a 兔 多克隆 antibody detecting PPIA in WB, IHC, ICC, FACS, IF 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5518864
发货至: 中国
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Quick Overview for PPIA 抗体 (AA 116-165) (ABIN5518864)

抗原

See all PPIA 抗体
PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PPIA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 116-165

    原理

    Anti-Cyclophilin A/PPIA Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Cyclophilin A/PPIA Antibody (ABIN5518864). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cyclophilin A recombinant protein (Position: T116-E165). Human Cyclophilin A shares 98% and 95.9% amino acid (aa) sequence identity with mouse and rat Cyclophilin A, respectively.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

    别名

    PPIA

    背景

    Synonyms: Peptidyl-prolyl cis-trans isomerase A,PPIase A,5.2.1.8,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A,Peptidyl-prolyl cis-trans isomerase A, N-terminally processed,PPIA,CYPA,

    Tissue Specificity: Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.

    Background: Cyclophilin A (PPIA), Peptidylprolyl isomerase A, is an enzyme that in humans is encoded by the PPIA gene. Using chromosome 7 and chromosome 10 deletion hybrid panels, the PPIA coding gene is localized to 7p13-p11.2. This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. Cyclophilin A is also a member of the immunophilin class of proteins that all possess peptidyl-prolyl cis/trans isomerase activity and are believed to be involved in protein folding and/or intracellular protein transport. And Cyclophilin A binds to the Gag protein of human immunodeficiency virus type 1 (HIV-1). Additionally, Cyclophilin A may have an essential function in HIV-1 replication.may have an essential function in HIV-1 replication.

    分子量

    185 kDa

    基因ID

    5478

    UniProt

    P62937
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