PIK3CB 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for PIK3CB 抗体 (Middle Region) (ABIN5518862)
抗原
See all PIK3CB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- Anti-PI3 Kinase p110 beta/PIK3CB Antibody
-
序列
- DLIWTLRQDC REIFPQSLPK LLLSIKWNKL EDVAQLQALL QIW
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- different from the related mouse,rat sequences by one amino acid.
-
产品特性
- Anti-PI3 Kinase p110 beta/PIK3CB Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PIK3CB, different from the related mouse and rat sequences by one amino acid.
-
亚型
- IgG
-
-
-
-
应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
-
: "The expression of S100B protein in serum of patients with brain metastases from small-cell lung cancer and its clinical significance." in: Oncology letters, Vol. 14, Issue 6, pp. 7107-7110, (2017) (PubMed).
: "Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 151-8, (2014) (PubMed).
-
-
- PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))
-
别名
- PIK3CB
-
背景
-
Background: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene. This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Gene Full Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
-
分子量
- 110 kDa
-
基因ID
- 5291
-
UniProt
- P42338
抗原
-