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PIK3CB 抗体 (Middle Region)

Cited in 2+ publications. The 兔 多克隆 anti-PIK3CB antibody (ABIN5518862) specifically detects PIK3CB in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5518862
发货至: 中国
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Quick Overview for PIK3CB 抗体 (Middle Region) (ABIN5518862)

抗原

See all PIK3CB 抗体
PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))

适用

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人, 小鼠, 大鼠

宿主

  • 124
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克隆类型

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多克隆

标记

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This PIK3CB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    原理

    Anti-PI3 Kinase p110 beta/PIK3CB Antibody

    序列

    DLIWTLRQDC REIFPQSLPK LLLSIKWNKL EDVAQLQALL QIW

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by one amino acid.

    产品特性

    Anti-PI3 Kinase p110 beta/PIK3CB Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PIK3CB, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Mu, Ma, Shi, Zhen: "The expression of S100B protein in serum of patients with brain metastases from small-cell lung cancer and its clinical significance." in: Oncology letters, Vol. 14, Issue 6, pp. 7107-7110, (2017) (PubMed).

    Wang, Sun, Li, Dong, Li, Zhao: "Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 151-8, (2014) (PubMed).

  • 抗原

    PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))

    别名

    PIK3CB

    背景

    Background: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene. This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.

    Gene Full Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

    分子量

    110 kDa

    基因ID

    5291

    UniProt

    P42338
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