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OTC 抗体 (N-Term)

OTC 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518860
发货至: 中国
  • 抗原 See all OTC 抗体
    OTC (Ornithine Carbamoyltransferase (OTC))
    抗原表位
    • 15
    • 11
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-70, N-Term
    适用
    • 39
    • 31
    • 24
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 49
    • 7
    克隆类型
    • 49
    • 7
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OTC antibody is un-conjugated
    应用范围
    • 45
    • 18
    • 15
    • 13
    • 13
    • 11
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Ornithine carbamoyltransferase, mitochondrial(OTC) detection. Tested with WB in Human,Mouse,Rat.
    序列
    NKVQLKGRDL LTLKNFTGEE IKYMLWLSAD LKFRIKQK
    交叉反应 (详细)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Ornithine carbamoyltransferase, mitochondrial(OTC) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: ornithine carbamoyltransferase
    Protein Name: Ornithine carbamoyltransferase, mitochondrial
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human OTC (33-70aa NKVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQK), different from the related mouse and rat sequences by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product OTC Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    OTC (Ornithine Carbamoyltransferase (OTC))
    别名
    OTC (OTC 产品)
    别名
    OCTD antibody, 2810428A13Rik antibody, AA589422 antibody, AW457381 antibody, OCT antibody, Plxn2 antibody, mKIAA0463 antibody, F1B16.13 antibody, F1B16_13 antibody, ORNITHINE CARBAMOYLTRANSFERASE antibody, ornithine carbamoyltransferase antibody, BA4351 antibody, PSPTO4164 antibody, PLXN2 antibody, AI265390 antibody, Sf antibody, spf antibody, si:dkey-19h21.3 antibody, ornithine carbamoyltransferase antibody, plexin A2 antibody, ornithine carbamoyltransferase ArgF antibody, ornithine transcarbamylase antibody, OTC antibody, Plxna2 antibody, Otc antibody, argF antibody, argF-2 antibody, atpD-2 antibody, CNC04300 antibody, PLXNA2 antibody, otc antibody
    背景
    Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi). This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may also play a role in that disease.

    Synonyms: OCTD | Otc | OTCase | P00480
    基因ID
    5009
    UniProt
    P00480
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