KRT8 抗体 (AA 107-325)
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北京 101111
Quick Overview for KRT8 抗体 (AA 107-325) (ABIN5518853)
抗原
See all KRT8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 107-325
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原理
- Anti-Cytokeratin 8/KRT8 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cytokeratin 8/KRT8 Antibody (ABIN5518853). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cytokeratin 8 recombinant protein (Position: D107-K325). Human Cytokeratin 8 shares 95.4% and 94.5% amino acid (aa) sequence identity with mouse and rat Cytokeratin 8, respectively.
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亚型
- IgG
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anti-Keratin 8 (KRT8) antibody
KRT8 适用: 人, 小鼠 WB, IHC, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal M20 unconjugated
anti-Keratin 8 (KRT8) (AA 92-393) antibodyKRT8 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) (AA 1-483) antibodyKRT8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) (pSer432) antibodyKRT8 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) (Ser726), (Ser731) antibodyKRT8 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) antibodyKRT8 适用: 人, 大鼠, 斑马鱼 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal H1 unconjugated
anti-Keratin 8 (KRT8) (AA 91-381) antibodyKRT8 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Keratin 8 (KRT8) antibodyKRT8 适用: 人, Cow, 兔, Pig, 绵羊 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal B22-1 unconjugated
anti-Keratin 8 (KRT8) (AA 391-483) antibodyKRT8 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8A5D12 unconjugated
anti-Keratin 8 (KRT8) (N-Term) antibodyKRT8 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KRT8 (Keratin 8 (KRT8))
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别名
- KRT8
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背景
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Synonyms: Keratin, type II cytoskeletal 8,Cytokeratin-8,CK-8,Keratin-8,K8,Type-II keratin Kb8,KRT8,CYK8,
Tissue Specificity: Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. .
Background: Keratin, type II cytoskeletal 8, also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 54 kDa, 56 kDa
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基因ID
- 3856
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UniProt
- P05787
抗原
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