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KRT8 抗体 (AA 107-325)

KRT8 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518853
发货至: 中国
  • 抗原 See all KRT8 抗体
    KRT8 (Keratin 8 (KRT8))
    抗原表位
    • 23
    • 16
    • 13
    • 11
    • 8
    • 6
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    AA 107-325
    适用
    • 253
    • 79
    • 75
    • 33
    • 33
    • 31
    • 30
    • 16
    • 14
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 136
    • 125
    • 3
    克隆类型
    • 133
    • 128
    • 1
    多克隆
    标记
    • 145
    • 21
    • 16
    • 9
    • 4
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    • 1
    • 1
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    This KRT8 antibody is un-conjugated
    应用范围
    • 171
    • 102
    • 100
    • 81
    • 69
    • 45
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    • 30
    • 29
    • 24
    • 19
    • 5
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    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Keratin, type II cytoskeletal 8(KRT8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Keratin, type II cytoskeletal 8(KRT8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: keratin 8
    Protein Name: Keratin, type II cytoskeletal 8
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Cytokeratin 8 recombinant protein (Position: D107-K325). Human Cytokeratin 8 shares 95.4% and 94.5% amino acid (aa) sequence identity with mouse and rat Cytokeratin 8, respectively.
    亚型
    IgG
    Top Product
    Discover our top product KRT8 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    KRT8 (Keratin 8 (KRT8))
    别名
    KRT8 (KRT8 产品)
    背景
    Keratin, type II cytoskeletal 8, also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

    Synonyms: Keratin, type II cytoskeletal 8 | Cytokeratin-8 | CK-8 | Keratin-8 | K8 | Type-II keratin Kb8 | KRT8 | CYK8 | P05787
    基因ID
    3856
    UniProt
    P05787
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