IGFBPI 抗体 (AA 69-259)
Quick Overview for IGFBPI 抗体 (AA 69-259) (ABIN5518851)
抗原
See all IGFBPI 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 69-259
-
原理
- Anti-IGFBP1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-IGFBP1 Antibody Picoband® (ABIN5518851). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human IGFBP1 recombinant protein (Position: A69-N259). Human IGFBP1 shares 67.8% and 69.3% amino acid (aa) sequence identity with mouse and rat IGFBP1, respectively.
-
亚型
- IgG
-
-
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 36-235) antibody
IGFBPI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 112-263) antibodyIGFBPI 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 112-262) antibodyIGFBPI 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 26-272) antibodyIGFBPI 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) antibodyIGFBPI 适用: 小鼠, 大鼠 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 36-235) antibodyIGFBPI 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D9 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 26-259) antibodyIGFBPI 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 156-170) antibodyVerified IGFBPI 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (AA 160-259) antibodyIGFBPI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 1 (IGFBPI) (C-Term) antibodyIGFBPI 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
1. Alitalo, T., Kontula, K., Koistinen, R., Aalto-Setala, K., Julkunen, M., Janne, O. A., Seppala, M., de la Chapelle, A.The gene encoding human low-molecular weight insulin-like growth-factor binding protein (IGF-BP25): regional localization to 7p12-p13 and description of a DNA polymorphism.Hum. Genet. 83: 335-338, 1989. 2. Brinkman, A., Groffen, C. A. H., Kortleve, D. J., Drop, S. L. S.Organization of the gene encoding the insulin-like growth factor binding protein IBP-1.Biochem. Biophys. Res. Commun. 157: 898-907, 1988. 3. Leu, J. I.-J., George, D. L.Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria.Genes Dev. 21: 3095-3109, 2007. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
-
别名
- IGFBP1
-
背景
-
Synonyms: Insulin-like growth factor-binding protein 1,IBP-1,IGF-binding protein 1,IGFBP-1,Placental protein 12,PP12,IGFBP1,IBP1,
Tissue Specificity: High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.
Background: IGFBP1, Insulin-like growth factor-binding protein 1, also known as placental protein 12 (PP12), is a protein that in humans is encoded by the IGFBP1 gene. The IGFBP1 gene has 4 exons and spans 5.9 kb. And the IGFBP1 gene is localized to 7p13-p12 by in situ hybridization. This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
-
分子量
- 30 kDa
-
基因ID
- 3484
-
UniProt
- P08833
-
途径
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding
抗原
-
