HTRA3 抗体 (C-Term)
Quick Overview for HTRA3 抗体 (C-Term) (ABIN5518848)
抗原
See all HTRA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-362, C-Term
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原理
- Anti-HtrA3 Antibody Picoband®
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序列
- FAIPSDRITR FLTEFQDKQI KDWKKRFIGI RMR
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HtrA3 Antibody Picoband® (ABIN5518848). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HtrA3, different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids.
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亚型
- IgG
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anti-HtrA Serine Peptidase 3 (HTRA3) (AA 112-144), (N-Term) antibody
HTRA3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2322 unconjugated
anti-HtrA Serine Peptidase 3 (HTRA3) (AA 344-453) antibodyHTRA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-HtrA Serine Peptidase 3 (HTRA3) antibodyHTRA3 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 3 (HTRA3) (AA 214-453) antibodyHTRA3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 3 (HTRA3) (AA 334-453) antibodyHTRA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 3 (HTRA3) antibodyHTRA3 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 3 (HTRA3) (Middle Region) antibodyHTRA3 适用: 人, 大鼠, 小鼠, 豚鼠, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Nie, G.-Y., Hampton, A., Li, Y., Findlay, J. K., Salamonsen, L. A. Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2. Biochem. J. 371: 39-48, 2003. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HTRA3 (HtrA Serine Peptidase 3 (HTRA3))
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别名
- HTRA3
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背景
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Synonyms: Serine protease HTRA3,3.4.21.-,High-temperature requirement factor A3,Pregnancy-related serine protease,HTRA3,PRSP,
Tissue Specificity: Widely expressed, with highest levels in both adult and fetal heart, ovary, uterus placenta, and bladder. In the endometrium, expressed in epithelial glands and the stroma. Also present in leukocytes. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney. .
Background: Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440)-binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.
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分子量
- 49 kDa
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基因ID
- 94031
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UniProt
- P83110
抗原
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