HFE 抗体 (AA 82-199)
Quick Overview for HFE 抗体 (AA 82-199) (ABIN5518842)
抗原
See all HFE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 82-199
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原理
- Anti-HFE Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HFE Antibody Picoband® (ABIN5518842). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HFE recombinant protein (Position: Q82-R199). Human HFE shares 72.2% and 74.6% amino acid (aa) sequence identity with mouse and rat HFE, respectively.
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亚型
- IgG
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anti-Hemochromatosis (HFE) (AA 115-205) antibody
HFE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Hemochromatosis (HFE) antibodyHFE 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Hemochromatosis (HFE) (AA 1-348) antibodyHFE 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 262-348) antibodyHFE 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (Internal Region) antibodyHFE 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 149-198) antibodyHFE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 80-306) antibodyHFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (C-Term) antibodyHFE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 35-84) antibodyHFE 适用: 人, 小鼠, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Hemochromatosis (HFE) (AA 1-348) antibodyHFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Martins, R, Silva, B, Proen99a, D, Faustino, P (3 March 2011). "Differential HFE gene expression is regulated by alternative splicing in human tissues". PLOS ONE. 6 (3): e17542. 2. Waheed, A, Parkkila, S, Saarnio, J, Fleming, RE, Zhou, XY, Tomatsu, S, Britton, RS, Bacon, BR, Sly, WS (16 February 1999). "Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum". Proceedings of the National Academy of Sciences of the United States of America. 96 (4): 1579-84. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HFE (Hemochromatosis (HFE))
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别名
- HFE
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背景
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Synonyms: Hereditary hemochromatosis protein,HLA-H,HFE,HLAH,
Tissue Specificity: Expressed in all tissues tested except brain.
Background: Human hemochromatosis protein also known as the HFE protein is a protein which in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p21.3. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.
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分子量
- 40 kDa
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基因ID
- 3077
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UniProt
- Q30201
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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