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GABBR1 抗体 (AA 186-405)

This 兔 多克隆 anti-GABBR1 antibody specifically detects GABBR1 in WB. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN5518835
发货至: 中国
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Quick Overview for GABBR1 抗体 (AA 186-405) (ABIN5518835)

抗原

See all GABBR1 抗体
GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GABBR1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 186-405

    原理

    Anti-GABA B Receptor 1/GABBR1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-GABA B Receptor 1/GABBR1 Antibody (ABIN5518835). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GABBR1 recombinant protein (Position: Q186-D405). Human GABBR1 shares 99.5% amino acid (aa) sequence identity with both mouse and rat GABBR1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

    别名

    GABBR1

    背景

    Synonyms: Gamma-aminobutyric acid type B receptor subunit 1,GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABABR1,Gb1,GABBR1,GPRC3A,

    Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .

    Background: Gamma-aminobutyric acid (GABA) B receptor, 1 (GABAB1), is a G-protein coupled receptor subunit encoded by the GABBR1 gene. This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA (B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.

    分子量

    108 kDa

    基因ID

    2550

    途径

    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
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