ECE1 抗体 (AA 18-233)
(1 reference)Quick Overview for ECE1 抗体 (AA 18-233) (ABIN5518828)
抗原
See all ECE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-233
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原理
- Anti-ECE1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ECE1 Antibody Picoband® (ABIN5518828). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ECE1 recombinant protein (Position: M18-T233). Human ECE1 shares 94% and 93.5% amino acid (aa) sequence identity with mouse and rat ECE1, respectively.
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亚型
- IgG
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anti-Endothelin-Converting Enzyme 1 (ECE1) antibody
ECE1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 665-770) antibodyECE1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 471-770) antibodyECE1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 1-770) antibodyECE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (N-Term) antibodyECE1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 528-556) antibodyECE1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17841 unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 528-556), (C-Term) antibodyECE1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) antibodyECE1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 670-770) antibodyECE1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endothelin-Converting Enzyme 1 (ECE1) (AA 469-721) antibodyECE1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Schmidt M, Kröger B, Jacob E, Seulberger H, Subkowski T, Otter R, Meyer T, Schmalzing G, Hillen H (December 1994). "Molecular characterization of human and bovine endothelin converting enzyme (ECE-1)". FEBS Lett. 356 (2-3): 238-43. 2. "Entrez Gene: ECE1 endothelin converting enzyme 1". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Endoplasmic reticulum stress promotes amyloid-beta peptides production in RGC-5 cells." in: Cell stress & chaperones, Vol. 19, Issue 6, pp. 827-35, (2014) (PubMed).
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: "Endoplasmic reticulum stress promotes amyloid-beta peptides production in RGC-5 cells." in: Cell stress & chaperones, Vol. 19, Issue 6, pp. 827-35, (2014) (PubMed).
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- ECE1 (Endothelin-Converting Enzyme 1 (ECE1))
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别名
- ECE1
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背景
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Synonyms: Endothelin-converting enzyme 1,ECE-1,3.4.24.71,ECE1,
Tissue Specificity: All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma, isoforms A and C in liver, testis and small intestine, isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells, isoforms C and D in saphenous vein cells, and isoform C in kidney. .
Background: Endothelin converting enzyme 1, also known as ECE1, is an enzyme which in humans is encoded by the ECE1 gene. The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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分子量
- 87 kDa
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基因ID
- 1889
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UniProt
- P42892
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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