CRX 抗体 (C-Term)
Quick Overview for CRX 抗体 (C-Term) (ABIN5518821)
抗原
See all CRX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 265-299, C-Term
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原理
- Anti-CORD2/CRX Antibody Picoband®
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序列
- DSLEFKDPTG TWKFTYNPMD PLDYKDQSAW KFQIL
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CORD2/CRX Antibody Picoband® (ABIN5518821). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CORD2, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Cone-Rod Homeobox (CRX) (AA 1-95) antibody
CRX 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 1-300) antibodyCRX 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal F6-C2 unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 120-285) antibodyCRX 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 1-299) antibodyCRX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A12 unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 51-150) antibodyCRX 适用: 大鼠, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 120-285) antibodyCRX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cone-Rod Homeobox (CRX) (Internal Region) antibodyVerified CRX 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 1-95) antibodyCRX 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cone-Rod Homeobox (CRX) (AA 294-297), (C-Term) antibodyCRX 适用: 人 WB 宿主: 兔 Polyclonal RB49208 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Freund CL, Gregory-Evans CY, Furukawa T, Papaioannou M, Looser J, Ploder L, Bellingham J, Ng D, Herbrick JA, Duncan A, Scherer SW, Tsui LC, Loutradis-Anagnostou A, Jacobson SG, Cepko CL, Bhattacharya SS, McInnes RR (Nov 1997). "Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor". Cell. 91 (4): 543-53. 2. Freund CL, Wang QL, Chen S, Muskat BL, Wiles CD, Sheffield VC, Jacobson SG, McInnes RR, Zack DJ, Stone EM (Apr 1998). "De novo mutations in the CRX homeobox gene associated with Leber congenital amaurosis". Nature Genetics. 18 (4): 311-2. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CRX (Cone-Rod Homeobox (CRX))
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别名
- CRX
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背景
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Synonyms: Cone-rod homeobox protein,CRX,CORD2,
Tissue Specificity: Retina.
Background: Cone-rod homeobox protein is a protein that in humans is encoded by the CRX gene. The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
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分子量
- 37 kDa
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基因ID
- 1406
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UniProt
- O43186
抗原
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