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CA4 抗体 (AA 19-284)

This anti-CA4 antibody is a 兔 多克隆 antibody detecting CA4 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5518815
发货至: 中国

Quick Overview for CA4 抗体 (AA 19-284) (ABIN5518815)

抗原

See all CA4 抗体
CA4 (Carbonic Anhydrase IV (CA4))

适用

  • 52
  • 18
  • 15
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 44
  • 27

克隆类型

  • 46
  • 25
多克隆

标记

  • 45
  • 7
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  • 2
  • 2
  • 2
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  • 1
This CA4 antibody is un-conjugated

应用范围

  • 53
  • 34
  • 24
  • 19
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  • 6
  • 2
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Western Blotting (WB)
  • 抗原表位

    • 13
    • 8
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    • 4
    • 2
    • 2
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    • 1
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    • 1
    AA 19-284

    原理

    Anti-Carbonic Anhydrase IV/CA4 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Carbonic Anhydrase IV/CA4 Antibody Picoband® (ABIN5518815). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CA IV recombinant protein (Position: A19-S284). Human CA IV shares 55.5% and 58.9% amino acid (aa) sequence identity with mouse and rat CA IV, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
    1. Okuyama T, Batanian JR, Sly WS (Aug 1993). "Genomic organization and localization of gene for human carbonic anhydrase IV to chromosome 17q". Genomics. 16 (3): 678-84. 2. Sterling D, Alvarez BV, Casey JR (Jul 2002). "The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV". J. Biol. Chem. 277 (28): 25239-46.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CA4 (Carbonic Anhydrase IV (CA4))

    别名

    CA4

    背景

    Synonyms: Carbonic anhydrase 4,4.2.1.1,Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV,CA4,

    Tissue Specificity: Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels. .

    Background: Carbonic anhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.

    分子量

    35 kDa

    基因ID

    762

    UniProt

    P22748
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