ARNTL 抗体 (AA 58-156)
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北京 101111
Quick Overview for ARNTL 抗体 (AA 58-156) (ABIN5518808)
抗原
See all ARNTL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 58-156
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原理
- Anti-BMAL1/ARNTL Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-BMAL1/ARNTL Antibody (ABIN5518808). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BMAL1/ARNTL recombinant protein (Position: H58-D156). Human BMAL1/ARNTL shares 99% and 98% amino acid (aa) sequence identity with mouse and rat BMAL1/ARNTL, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
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别名
- ARNTL
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背景
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Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 1,Basic-helix-loop-helix-PAS protein MOP3,Brain and muscle ARNT-like 1,Class E basic helix-loop-helix protein 5,bHLHe5,Member of PAS protein 3,PAS domain-containing protein 3,bHLH-PAS protein JAP3,ARNTL,BHLHE5, BMAL1, MOP3, PASD3,
Tissue Specificity: Hair follicles (at protein level). Highly expressed in the adult brain, skeletal muscle and heart. .
Background: Aryl hydrocarbon receptor nuclear translocator-like protein 1 is protein that in humans is encoded by the ARNTL gene. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 75 kDa
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基因ID
- 406
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UniProt
- O00327
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途径
- Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
抗原
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