AQP6 抗体 (C-Term)
Quick Overview for AQP6 抗体 (C-Term) (ABIN5518807)
抗原
See all AQP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 238-271, C-Term
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原理
- Anti-Aquaporin 6/AQP6 Antibody Picoband®
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序列
- DTKTLAQRLA ILTGTVEVGT GAGAGAEPLK KESQ
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Aquaporin 6/AQP6 Antibody Picoband® (ABIN5518807). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6, different from the related mouse and rat sequences by fourteen amino acids.
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亚型
- IgG
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anti-Aquaporin 6, Kidney Specific (AQP6) (AA 1-30) antibody
AQP6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 6, Kidney Specific (AQP6) (Internal Region) antibodyAQP6 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 6, Kidney Specific (AQP6) (AA 264-282), (C-Term) antibodyAQP6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 6, Kidney Specific (AQP6) (AA 259-276), (Intracellular) antibodyAQP6 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. "Entrez Gene: Aquaporin 6, kidney specific". 2. Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., Yasui, M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc. Nat. Acad. Sci. 102: 2192-2197, 2005. 3. Ma, T., Yang, B., Umenishi, F., Verkman, A. S. Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. Genomics 43: 387-389, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- AQP6 (Aquaporin 6, Kidney Specific (AQP6))
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别名
- AQP6
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背景
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Synonyms: Aquaporin-6,AQP-6,Aquaporin-2-like,Kidney-specific aquaporin,hKID,AQP6,AQP2L,
Background: Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.
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分子量
- 29 kDa
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基因ID
- 363
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UniProt
- Q13520
抗原
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