ALDH1A3 抗体 (AA 37-154)
Quick Overview for ALDH1A3 抗体 (AA 37-154) (ABIN5518802)
抗原
See all ALDH1A3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 37-154
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原理
- Anti-ALDH1A3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ALDH1A3 Antibody Picoband® (ABIN5518802). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ALDH1A3 recombinant protein (Position: N37-K154). Human ALDH1A3 shares 89% and 87.3% amino acid (aa) sequence identity with mouse and rat ALDH1A3, respectively.
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亚型
- IgG
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anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (AA 1-100), (AA 413-512) antibody
ALDH1A3 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (AA 332-509) antibodyALDH1A3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (AA 2-210) antibodyALDH1A3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (Internal Region) antibodyALDH1A3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (AA 318-348) antibodyALDH1A3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16820 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (AA 24-51), (N-Term) antibodyALDH1A3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16818 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (AA 1-140) antibodyALDH1A3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (N-Term) antibodyALDH1A3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Nishimura M, Yoshitsugu H, Naito S, Hiraoka I (2002). "Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR.". Yakugaku Zasshi. 122 (5): 339-61. 2. Rexer BN, Zheng WL, Ong DE (2001). "Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells.". Cancer Res. 61 (19): 7065-70. 3. Yoshida A, Rzhetsky A, Hsu LC, Chang C (1998). "Human aldehyde dehydrogenase gene family.". Eur. J. Biochem. 251 (3): 549-57. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))
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别名
- ALDH1A3
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背景
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Synonyms: Aldehyde dehydrogenase family 1 member A3,1.2.1.5,Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RALDH-3,RalDH3,ALDH1A3,ALDH6,
Tissue Specificity: Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Background: Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
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分子量
- 56 kDa
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基因ID
- 220
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UniProt
- P47895
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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