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TRF2 抗体 (AA 81-287)

This anti-TRF2 antibody is a 兔 多克隆 antibody detecting TRF2 in WB 和 IHC. Suitable for 人 和 大鼠.
产品编号 ABIN5518791
发货至: 中国

Quick Overview for TRF2 抗体 (AA 81-287) (ABIN5518791)

抗原

See all TRF2 (TERF2) 抗体
TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TRF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 81-287

    原理

    Anti-TRF2/TERF2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-TRF2/TERF2 Antibody Picoband® (ABIN5518791). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TRF2 recombinant protein (Position: A81-K287). Human TRF2 shares 95.7% amino acid (aa) sequence identity with mouse TRF2.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. "Entrez Gene: TERF2 telomeric repeat binding factor 2". 2. Opresko PL, von Kobbe C, Laine JP, Harrigan J, Hickson ID, Bohr VA (October 2002). "Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases". J. Biol. Chem. 277 (43): 41110-9. 3. Sakaguchi, A. Y., Padalecki, S. S., Mattern, V., Rodriguez, A., Leach, R. J., McGill, J. R., Chavez, M., Giambernardi, T. A. (1998-05-01). "Chromosomal sublocalization of the transcribed human telomere repeat binding factor 2 gene and comparative mapping in the mouse". Somatic Cell and Molecular Genetics. 24 (3): 157-163.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

    别名

    TERF2

    背景

    Synonyms: Telomeric repeat-binding factor 2,TTAGGG repeat-binding factor 2,Telomeric DNA-binding protein,TERF2,TRBF2, TRF2,

    Tissue Specificity: Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.

    Background: Telomeric repeat-binding factor 2, also known as TERF2, TRF2, or TRBF2, is encoded in humans by the TERF2 gene. This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

    分子量

    75 kDa

    基因ID

    7014

    UniProt

    Q15554

    途径

    Cell Division Cycle, Telomere Maintenance
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