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PPL 抗体 (C-Term)

PPL 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Periplakin expression in rat stomach extract ( Lane 1) and HELA whole cell lysates ( Lane 2). (PPL 抗体 (C-Term))

Periplakin was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- Periplakin Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (PPL 抗体 (C-Term))

Periplakin was detected in paraffin-embedded sections of human oesophagus squama cancer tissues using rabbit anti- Periplakin Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (PPL 抗体 (C-Term))

Periplakin was detected in paraffin-embedded sections of human tonsil tissues using rabbit anti- Periplakin Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (PPL 抗体 (C-Term))

Periplakin was detected in paraffin-embedded sections of mouse lung tissues using rabbit anti- Periplakin Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (PPL 抗体 (C-Term))

Periplakin was detected in paraffin-embedded sections of rat lung tissues using rabbit anti- Periplakin Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (PPL 抗体 (C-Term))

Periplakin was detected in paraffin-embedded sections of rat skin tissues using rabbit anti- Periplakin Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (PPL 抗体 (C-Term))

7 images

产品编号 ABIN5518787

发货至: 中国

Datasheet as PDF

抗原 See all PPL 抗体

PPL (Periplakin (PPL))
抗原表位
8

6

3

2

2

2

1

1

1

1

1
AA 1664-1701, C-Term
适用
32

9

5

1
人, 小鼠, 大鼠
宿主
34

2
兔
Compatible Secondaries
克隆类型
36
多克隆
标记
27

3

2

2

1

1
This PPL antibody is un-conjugated
应用范围
34

24

11

10

9

5

4

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

原理

Anti-Periplakin/PPL Antibody Picoband®

序列

DTGRELSPEE AHRAGLIDWN MFVKLRSQEC DWEEISVK

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Periplakin/PPL Antibody Picoband® (ABIN5518787). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Periplakin, different from the related mouse sequence by one amino acid.

亚型

IgG
anti-Periplakin (PPL) (AA 1664-1701) antibody
PPL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1-130) antibody
PPL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1501-1754) antibody
PPL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) antibody
PPL 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) antibody
PPL 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1-130) antibody
PPL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1439-1716) antibody
PPL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1301-1330), (C-Term) antibody
PPL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1-100) antibody
PPL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Periplakin (PPL) (AA 1-100) antibody (Biotin)
PPL 适用: 人 WB 宿主: 兔 Polyclonal Biotin

应用备注

Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. "Entrez Gene: PPL periplakin". 2. Aho S, McLean WH, Li K, Uitto J (Jun 1998). "cDNA cloning, mRNA expression, and chromosomal mapping of human and mouse periplakin genes". Genomics. 48 (2): 242-7. 3. Kazerounian, Shideh, Uitto Jouni, Aho Sirpa (Oct 2002). "Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentin". Exp. Dermatol. Denmark. 11(5): 428-38.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PPL (Periplakin (PPL))

别名

PPL (PPL 产品)

背景

Synonyms: Periplakin,190 kDa paraneoplastic pemphigus antigen,195 kDa cornified envelope precursor protein,PPL,KIAA0568,
Tissue Specificity: Expressed in stratified squamous epithelia and in some other epithelia. .
Background: Periplakin is a protein that in humans is encoded by the PPL gene. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

分子量

202 kDa

基因ID

5493

UniProt

O60437

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