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LMO1 抗体 (C-Term)

This anti-LMO1 antibody is a 兔 多克隆 antibody detecting LMO1 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5518772
发货至: 中国

Quick Overview for LMO1 抗体 (C-Term) (ABIN5518772)

抗原

See all LMO1 抗体
LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))

适用

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人, 大鼠, 小鼠

宿主

  • 25
  • 6

克隆类型

  • 25
  • 6
多克隆

标记

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This LMO1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 127-156, C-Term

    原理

    Anti-LMO1 Antibody Picoband®

    序列

    DKFFLKNNMI LCQMDYEEGQ LNGTFESQVQ

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-LMO1 Antibody Picoband® (ABIN5518772). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human LMO1, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)". 2. Boehm T, Foroni L, Kaneko Y, Perutz MF, Rabbitts TH (June 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. 88 (10): 4367-71. 3. McGuire EA, Davis AR, Korsmeyer SJ (March 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. 77 (3): 599-606.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))

    别名

    LMO1

    背景

    Synonyms: Rhombotin-1,Cysteine-rich protein TTG-1,LIM domain only protein 1,LMO-1,T-cell translocation protein 1,LMO1,RBTN1, RHOM1, TTG1,

    Tissue Specificity: Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. .

    Background: Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene. This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions, thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

    分子量

    18 kDa

    基因ID

    4004

    UniProt

    P25800

    途径

    Dopaminergic Neurogenesis
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