LMO1 抗体 (C-Term)
Quick Overview for LMO1 抗体 (C-Term) (ABIN5518772)
抗原
See all LMO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 127-156, C-Term
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原理
- Anti-LMO1 Antibody Picoband®
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序列
- DKFFLKNNMI LCQMDYEEGQ LNGTFESQVQ
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-LMO1 Antibody Picoband® (ABIN5518772). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human LMO1, different from the related mouse sequence by two amino acids.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)". 2. Boehm T, Foroni L, Kaneko Y, Perutz MF, Rabbitts TH (June 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. 88 (10): 4367-71. 3. McGuire EA, Davis AR, Korsmeyer SJ (March 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. 77 (3): 599-606. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))
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别名
- LMO1
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背景
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Synonyms: Rhombotin-1,Cysteine-rich protein TTG-1,LIM domain only protein 1,LMO-1,T-cell translocation protein 1,LMO1,RBTN1, RHOM1, TTG1,
Tissue Specificity: Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. .
Background: Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene. This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions, thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.
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分子量
- 18 kDa
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基因ID
- 4004
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UniProt
- P25800
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途径
- Dopaminergic Neurogenesis
抗原
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