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ITGAL 抗体 (AA 161-349)

ITGAL 适用: 人 FACS, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518766
发货至: 中国
  • 抗原 See all ITGAL 抗体
    ITGAL (Integrin alpha-L (ITGAL))
    抗原表位
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 161-349
    适用
    • 122
    • 65
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 93
    • 60
    • 38
    • 1
    克隆类型
    • 138
    • 53
    • 1
    多克隆
    标记
    • 66
    • 27
    • 26
    • 19
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGAL antibody is un-conjugated
    应用范围
    • 125
    • 49
    • 34
    • 29
    • 27
    • 25
    • 23
    • 21
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Integrin alpha-L(ITGAL) detection. Tested with WB, FCM in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Integrin alpha-L(ITGAL) detection. Tested with WB, FCM in Human.
    Gene Name: integrin subunit alpha L
    Protein Name: Integrin alpha-L
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human CD11a recombinant protein (Position: F161-L349). Human CD11a shares 73.7% mino acid (aa) sequence identity with mouse CD11a.
    亚型
    IgG
    Top Product
    Discover our top product ITGAL Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Flow Cytometry: Concentration: 1-3 μg/1x106 cells, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Mu, Jing, Guo: "Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." in: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).

  • 抗原
    ITGAL (Integrin alpha-L (ITGAL))
    别名
    ITGAL (ITGAL 产品)
    别名
    CD11A antibody, LFA-1 antibody, LFA1A antibody, (p180) antibody, Cd11a antibody, LFA-1A antibody, Ly-15 antibody, Ly-21 antibody, CD11a antibody, ITGAL antibody, integrin subunit alpha L antibody, integrin alpha L antibody, ITGAL antibody, Itgal antibody
    背景
    CD11a, also known as ITGAL or LFA-1, is a human gene which functions in the immune system. It is mapped to 16p11.2. CD11a is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. CD11a encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. It is one of the two components, along with CD18, which form lymphocyte function-associated antigen-1.

    Synonyms: Antigen CD11A | CD 11a | CD11 antigen-like family member A | CD11a antigen | Integrin alphaL | Integrin alpha-L | ITAL | ITGAL protein | LFA 1A | LFA1A | LFA-1A | P20701
    基因ID
    3683
    UniProt
    P20701
    途径
    Activated T Cell Proliferation, Integrin Complex
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