HBV Large S Protein 抗体 (N-Term)
(4 references)Quick Overview for HBV Large S Protein 抗体 (N-Term) (ABIN5518758)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-51, N-Term
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原理
- Anti-Hepatitis B Virus Antibody Picoband®
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序列
- WSSKPRQGMG TNLSVPNPLG FFPDHQLDPA FGANSNNPDW DFNPNKDQ
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
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Rabbit IgG polyclonal antibody for Large S protein(S) detection. Tested with WB, IHC-P in Human,HBV.
Gene Name: long surface protein, PreS1, L protein, LHBs, large S protein, pre-S1/pre-S2/S regions, L glycoprotein, L-HBsAG, LHBs
Protein Name: Large S protein -
纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Hepatitis B Virus.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, HBV
1. Magnius LO, Norder H (1995). "Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene". Intervirology. 38 (1-2): 24-34. 2. Rysgaard, Carolyn D, Morris, Cory S, Drees, Denny, Bebber, Tami, Davis, Scott R, Kulhavy, Jeff, Krasowski, Matthew D (2012). "Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem". BMC Clinical Pathology. 12 (1): 15. doi:10.1186/1472-6890-12-15. Retrieved11 March 2014. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth." in: Journal of viral hepatitis, Vol. 18, Issue 9, pp. 653-60, (2011) (PubMed).
: "Expression of transforming growth factor-alpha and hepatitis B surface antigen in human hepatocellular carcinoma tissues and its significance." in: World journal of gastroenterology, Vol. 10, Issue 6, pp. 830-3, (2004) (PubMed).
: "Passive limitation of adduction after Cüppers's 'Fadenoperation' on medial recti." in: The British journal of ophthalmology, Vol. 73, Issue 8, pp. 633-5, (1989) (PubMed).
: "Should medicine today be taught without medical ethics?" in: Connecticut medicine, Vol. 37, Issue 8, pp. 420-1, (1973) (PubMed).
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: "Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth." in: Journal of viral hepatitis, Vol. 18, Issue 9, pp. 653-60, (2011) (PubMed).
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- HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))
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别名
- S
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物质类
- Viral Protein
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背景
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Synonyms: Large S protein ,S ,
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: Hepatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. It consists of HBsAg, HBcAg (HBeAg is a splice variant), Hepatitis B virus DNA polymerase and HBx. Among these, HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). It indicates current hepatitis B infection. The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.
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分子量
- 6 kDa
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UniProt
- D2X4M3
抗原
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